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Novavax vaccine – Development and deployment stages explained
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Novavax vaccine – Development and deployment stages explained

Novavax’s COVID-19 vaccine is known by several names globally, including NVX-CoV2373 and Nuvaxovid in some regions. The vaccine uses a tiny piece of the SARS-CoV-2 virus’s spike protein as its primary antigen. This spike protein is the part of the virus that lets it enter human cells and enhance the body’s immune response. The vaccine further includes an adjuvant called Matrix-M. Here are a few details about the vaccine’s development and deployment. Preclinical development Novavax began developing the vaccine in early 2020 utilizing its nanoparticle technology platform. The company identified a stabilized SARS-CoV-2 spike protein as its antigen and combined it with an adjuvant (Matrix-M) to enhance the immune response. Phase 1 and phase 2 trials Novavax initially conducted clinical trials in two phases to evaluate the vaccine’s safety and immunogenicity. These trials involved a relatively small number of participants and aimed to determine the appropriate dosage. Phase 3 clinical trials In the latter half of 2020 and early 2021, Novavax initiated large-scale phase 3 clinical trials to assess the vaccine’s efficacy in preventing COVID-19. These trials involved thousands of participants in multiple countries. Authorization and approval The Novavax vaccine, like other COVID-19 vaccines, required regulatory authorization or approval by a country’s authorities before it could be used.
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5 natural ways to delay a period
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5 natural ways to delay a period

The inconvenience of having a menstrual period coincide with important events, vacations, or other life activities cannot be overstated. Some might choose to just deal with it, while others might want to look for natural ways to delay a period by a few days. Here are some natural ways that women have tried to delay their period; however, note that these methods have little scientific backing, so individual results may vary. Food Changes According to some anecdotes, the menstrual cycle can be influenced by food choices. Consuming foods rich in vitamin C, can help delay menstruation. Vitamin C increases the production of progesterone, a hormone that can delay the onset of menstruation. Citrus fruits, broccoli, and strawberries are all excellent sources of vitamin C, as is lime juice. Herbal Teas Certain herbal teas like chamomile and ginger could also help postpone menstruation. These teas can have a calming effect on the uterus. Drinking a cup or two daily a few days before the expected period may be effective in delaying it naturally. Gram lentils Although there are anecdotal claims that the consumption of lentils made from gram flour a few days before menstruation might delay its onset, it’s important to note that these reports lack scientific evidence.
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6 first-line treatments for atopic dermatitis in infants
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6 first-line treatments for atopic dermatitis in infants

Eczema or atopic dermatitis is a skin condition that causes pain, itching, irritation, and inflammation. It can affect people of all ages, even infants. The first-line treatment for atopic dermatitis (eczema) in infants typically involves a combination of basic skincare and topical ointments. It’s essential to consult with a pediatrician or dermatologist for a personalized treatment plan before applying or considering any of the following options. Emollients (Moisturizers) One of the main problems of developing eczema is dry skin. So, keeping the skin well-hydrated is crucial. Dermatologists suggest applying a fragrance-free, hypoallergenic moisturizer or emollient to the affected areas at least twice daily and more often if needed. One should choose products that are specifically formulated for sensitive skin, as infants have soft skin that can easily develop a rash. Take care while bathing the infant Identify and avoid potential triggers, such as harsh soaps, that can exacerbate the condition. Dermatologists advise using lukewarm water for baths and suggest limiting the duration to 5-10 minutes maximum. Hot water is not advisable as it can dry out the child’s skin. Experts suggest using a mild, fragrance-free, hypoallergenic soap or cleanser for regular bathing. Also, later on, it’s important to gently pat the skin dry and not rub to prevent skin irritation.
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11 common signs of eosinophilic esophagitis
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11 common signs of eosinophilic esophagitis

Eosinophilic esophagitis (EoE) is an inflammatory disorder affecting the esophagus, the muscular tube that connects the throat to the stomach. This condition is characterized by the accumulation of eosinophils, a type of white blood cell, in the esophageal tissue, which results in inflammation, scarring, and narrowing of the esophagus. Early diagnosis and timely intervention are important for effective management of EoE. This article discusses common signs and symptoms of EoE. Read on to learn more. Common signs of eosinophilic esophagitis Dysphagia (Difficulty swallowing) One of the hallmark signs of eosinophilic esophagitis is difficulty swallowing, a condition known as dysphagia. Individuals with EoE often experience the sensation that food is getting stuck in their throat or chest, making it challenging to swallow solid and liquid foods. This can lead to prolonged mealtimes and a fear of eating. Food impaction In severe cases, EoE can cause food impaction, which is when food gets stuck in the esophagus and requires medical intervention. Symptoms may include severe chest pain, difficulty swallowing, and a sensation of choking. Reflux symptoms EoE can mimic the symptoms of gastroesophageal reflux disease (GERD). Individuals may experience heartburn, regurgitation, and acid reflux. These symptoms may be particularly troublesome at night.
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9 warning signs of amyloidosis
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9 warning signs of amyloidosis

Amyloidosis is a condition that develops when a protein called amyloid builds up in the organs, making them unable to function properly. It is an uncommon illness that often progresses silently before reaching an advanced stage. So, recognizing its signs is crucial for an early diagnosis and treatment. While the symptoms may vary depending on the affected organ, here are a few early warning signs of amyloidosis one should know: Unexplained fatigue One of the early signs of amyloidosis is persistent and unexplained fatigue. Here, one may feel unusually tired despite getting adequate rest. This symptom can interfere with the daily routine and should be examined by a doctor if it persists. Swelling and fluid retention Amyloidosis can lead to the accumulation of abnormal proteins in various organs, including the kidneys. This can result in fluid retention, causing swelling, especially in the ankles and legs. Recognizing this symptom is crucial for seeking early intervention. Shortness of breath As amyloid deposits can affect the heart and lungs, one may experience shortness of breath even when engaging in low-intensity physical activities. This symptom should not be ignored, as it could be indicative of a heart issue brought on by amyloidosis. Gastrointestinal issues Amyloid deposits along the gastrointestinal tract can slow down the movement of food through the intestines, interfering with digestion and causing issues like less appetite, nausea, diarrhea, and stomach aches.
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5 overlapping silent symptoms of Parkinson’s and TD
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5 overlapping silent symptoms of Parkinson’s and TD

Parkinson’s disease and Tardive Dyskinesia (TD) are neurological conditions that often hide in plain sight. While some of their symptoms are well-known, there are also silent signs that overlap, making early diagnosis a challenge. This article delves into five such subtle yet crucial symptoms that Parkinson’s and TD share, shedding light on the importance of recognizing these early warning signs for timely intervention and improved quality of life. Here are the five silent symptoms of Parkinson’s and TD that overlap: Tremors Tremors are perhaps the most well-known symptom of Parkinson’s disease, but they can also occur in TD. These involuntary, rhythmic movements of the hands, fingers, or other body parts can be subtle in the early stages, resembling a slight shiver or nervousness. Many people dismiss these tremors as a natural response to stress or fatigue, delaying a proper diagnosis. Muscle stiffness Both Parkinson’s and TD can cause muscle stiffness or rigidity. This symptom can be mistaken for the effects of aging or simple muscle fatigue. Individuals may notice that their movements become less fluid and more rigid over time, leading to difficulty with tasks that once felt effortless. Changes in facial expressions Parkinson’s and TD can affect facial expressions, making them appear mask-like or rigid.
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9 unusual signs of blood clots
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9 unusual signs of blood clots

Clotting is an essential function to control bleeding, but it can also cause health issues. When clots develop internally, their symptoms are not always as obvious. While it may result in visible signs like pain and redness in the affected area, a few unusual symptoms may also indicate the presence of a clot. Understanding these less typical signs is crucial for early detection and prompt action. So here are a few unusual signs to know: 1. Shortness of breath One of the less recognized signs of a blood clot is unexplained shortness of breath. Blood clots in the lungs, known as pulmonary embolisms, can obstruct blood flow and oxygen exchange. This can lead to sudden breathlessness, chest pain, and a rapid heart rate, all of which require prompt medical intervention. 2. Sharp pain in the side or back A sharp, stabbing pain in the side or back can indicate a kidney or abdominal blood clot. Clotting in these areas can disrupt organ function and cause intense discomfort. Persistent, unexplained pain should prompt one to seek medical attention. 3. Intense headaches Severe and unrelenting headaches can sometimes be linked to blood clots. Cerebral venous sinus thrombosis (CVST) is a rare condition where blood clots form in the brain’s venous sinuses.
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7 early symptoms of gastric cancer
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7 early symptoms of gastric cancer

Gastric or stomach cancer is a severe condition affecting thousands of individuals yearly. While it often goes undetected in its early stages, recognizing the warning signs is crucial for early intervention and timely treatment. Here are a few early symptoms of gastric cancer that individuals should be aware of. By recognizing these signs, individuals can seek prompt consultation with a healthcare professional, potentially increasing their chances of successful treatment and recovery. Persistent indigestion and heartburn One of the earliest signs of gastric cancer is persistent indigestion and heartburn. While occasional discomfort after a large meal is normal, prolonged and recurring indigestion may signal an underlying issue. If an individual experiences frequent heartburn that doesn’t improve with over-the-counter remedies or changes in meals, it’s essential to consult a healthcare professional for a thorough evaluation. Loss of appetite A sudden and persistent loss of appetite can be a concerning early symptom of gastric cancer. Individuals experiencing a notable decrease in their desire to eat, especially with other unusual symptoms, should seek medical attention promptly. It’s important to distinguish this from temporary loss of appetite due to illness or stress and consult a healthcare provider for a comprehensive evaluation. Abdominal pain and discomfort Persistent abdominal pain, particularly in the upper abdomen, can indicate gastric cancer.
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3 signs of weak immunity and ways to boost it against respiratory viruses like SARS-COV
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3 signs of weak immunity and ways to boost it against respiratory viruses like SARS-COV

The immune system is a complex network of cells, tissues, and organs that work together to defend the body against harmful invaders, such as pathogens (disease-causing microorganisms), abnormal cells, and foreign substances. Its primary function is to protect the body from infections and diseases. Weak immunity presents some evident issues that one shouldn’t ignore. Here is an overview of the signs and what can be done to manage low immunity. 1. Frequent infections and fatigue Individuals with weakened immunity are always at risk of recurrent infections like colds and sinusitis caused by respiratory viruses, as well as urinary tract and skin infections. Their healing is compromised as common wounds like cuts, bruises, and injuries take longer to heal than usual. All this leads to persistent tiredness that significantly affects a person’s quality of life. 2. Allergies and autoimmune responses An overactive or dysfunctional immune system triggers allergies that manifest as allergic rhinitis, asthma, or skin reactions. Frequent mouth or genital ulcers also indicate an underlying concern that shouldn’t be ignored. The immune system can also mistakenly attack healthy cells and tissues, leading to the development of autoimmune diseases like rheumatoid arthritis, lupus, and multiple sclerosis. Further, chronic gastrointestinal issues like diarrhea, bloating, or frequent infections in the gut can be linked to a compromised immune system.
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9 healthy and easy breakfast recipes to try
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9 healthy and easy breakfast recipes to try

Amidst the hustle and bustle of modern life, preparing a breakfast dish that is delectable, nourishing, and easy to prepare can be quite challenging. When it comes to starting the day on the right foot, people often need quick and easy breakfast options. This article lists nine mouthwatering breakfast recipes that cater to diverse tastes and preferences. Whether individuals prefer sweet or savory morning meals, these recipes provide a range of delightful choices: 1. Classic scrambled eggs One can opt for classic scrambled eggs to begin the day with a protein-packed breakfast. Beat the eggs, season with salt and pepper, and then cook the mixture in a non-stick pan with a touch of butter. For a unique twist, top with ingredients like cheese, spinach, or diced tomatoes. 2. Overnight oats For those with busy mornings, overnight oats offer a convenient solution. Mix rolled oats with yogurt, milk, and sweeteners such as honey or maple syrup. Before refrigerating overnight, add a final touch with berries and nuts for a quick and nutritious breakfast. 3. Avocado toast Avocado toast, a trendy and satisfying breakfast option, comes together in just a few minutes. Mash a ripe avocado onto whole-grain toast and add a pinch of salt, pepper, and a drizzle of olive oil to enhance the flavor.
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5 mistakes to avoid when investing in a high dividend ETF
finance

5 mistakes to avoid when investing in a high dividend ETF

Exchange-traded funds (ETF) have been gaining popularity in the investment sector for some time now. Along with mutual funds, they have been one of the most preferred investment options among investors. With investors having pumped in billions of dollars in ETFs by now, these funds sure seem like a lucrative investment avenue. However, financial experts suggest treading this path carefully so as to avoid unforeseeable losses. Here are a few mistakes that you can avoid while investing in high dividend ETFs: Overlooking long-term investment Looking at long-term goals is the golden rule when it comes to any type of investment. However, seasoned investors invest in ETFs on a short-term basis through a type of trading called intraday trade. This type of trading allows the investors to buy and sell stocks and other investments on the same day. However, if not thought out carefully, investing in high dividend ETFs through intraday trading can result in lower returns and higher trading costs. Buying an ETF simply based on its name This is one of the most common mistakes people make when investing in high dividend ETFs. Investors may think that an ETF’s name provides an insight into its investment reach, i.e., whether the ETF has local or/and global investors. However, this is a ploy that ETF issuers often use to lure investors. Investing in an ETF based solely on its name can lead to disastrous investments. So understand an ETF’s underlying holdings and market objectives before making an investment. Investing in the wrong ETF Like every investment, almost every ETF is vulnerable to market trends and economic slowdowns. However, this does not mean that the particular ETF has failed. When an ETF liquidates, you might still receive some money (termination and other fees might be levied). But this may take a while and you may lose out on the time that could have otherwise been utilized to make other investments.
How to qualify for a reverse mortgage
finance

How to qualify for a reverse mortgage

A reverse mortgage provides the elderly access to equity in their homes and supplements their income. With its flexible repayment option, it gives homeowners more control over their money. However, the government has laid out strict rules and guidelines concerning reverse mortgage eligibility criteria. So, if you’re considering a reverse mortgage, read on to know the reverse mortgage eligibility criteria and the types of reverse mortgages. Reverse mortgage eligibility criteria The first criterion for a reverse mortgage is that the primary homeowner must be at least 62 years of age. If your spouse is under the age of 62, you might still be eligible if you meet other reverse mortgage eligibility criteria. If you’re not 62 or older than 62, then you won’t qualify for a reverse mortgage even if you satisfy the criteria mentioned below. You must be the primary resident of the home you’re seeking a reverse mortgage for. Note that vacation homes or rental properties do not qualify. You must either entirely own the house or have at least 50% equity in it. If you have any mortgage balance remaining while applying for a reverse mortgage, you must be in a financial position to pay off that balance. You must not be late or overdue on any debt from the federal government. This includes income taxes and federal student loans. If you have to pay off such debts, you may very well use the money from the reverse mortgage loan to settle these debts. You must already have enough money, or be willing to use the money from the reverse mortgage loan to pay property taxes, insurance, and home maintenance and repair costs. You must meet a Department of Housing and Urban Development (HUD)-approved reverse mortgage counselor to understand how a reverse mortgage works. During the counseling, the counselor will review your eligibility for a reverse mortgage loan and inform you of the financial ramifications associated with a reverse mortgage.
5 benefits of opting for debt settlement
finance

5 benefits of opting for debt settlement

Debt settlement can be a financial lifesaver for many. Managing debt is quite a difficult task. With every advancing payment due date, one may feel their finances getting tighter and tighter. Between paying for a house mortgage, student loans, credit card debt, personal loans, and many other debts, it is quite common to miss out on paying one payment. Although it may not seem like a big problem initially, this is not good for financial health in the long term. This is where debt settlement comes in. There are multiple benefits to availing debt settlement offered by some of the top 10 debt settlement companies. No more bills With debt settlement, no more bills will be incoming in the mailbox. Debt settlement results in the closure of a debt account by the creditor. In such cases, one will not be able to use their credit cards again. However, this can be beneficial since it will prevent further debt in the future. With debt settlement, there is a permanent erasure of debt. No more collection calls With mounting debt, the calls of creditors are always incessant. If one if falling behind on too many bills, they are bound to be subjected to creditor calls throughout the day. This can add to the stress of not being able to clear away all the dues. Plus, many collection departments are not known to be kind on calls. When a debt settlement is opted for, it will stop the incessant calls from the various collection departments. No bankruptcy risk Rather than filing for bankruptcy, debt settlement is a better option. With the bankruptcy filing, credit score can deteriorate quite significantly. In some cases, the credit score has slid down by nearly 200 points, taking a good credit score to bad credit score. The credit score lowers with debt settlement too.